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1

The Questionable Benefits of Exchanging Saturated Fat With Polyunsaturated Fat

Ravnskov, Uffe, DiNicolantonio, James J., Harcombe, Zoë, Kummerow, Fred A., Okuyama, Harumi, Worm, Nicolai

Journal:

Mayo Clinic Proceedings

Year:

2014

Language:

english

File:

PDF, 163 KB

english, 2014

2

Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms

Okuyama, Harumi, Langsjoen, Peter H, Hamazaki, Tomohito, Ogushi, Yoichi, Hama, Rokuro, Kobayashi, Tetsuyuki, Uchino, Hajime

Journal:

Expert Review of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

3

No scientific support for linking dietary saturated fat to CHD

Ravnskov, Uffe, Diamond, David, Canan Efendigil Karatay, M., Miller, Donald W., Okuyama, Harumi

Journal:

British Journal Of Nutrition

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

4

Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes

Okuyama, Harumi, Langsjoen, Peter H., Ohara, Naoki, Hashimoto, Yoko, Hamazaki, Tomohito, Yoshida, Satoshi, Kobayashi, Tetsuyuki, Langsjoen, Alena M.

Journal:

Year:

2016

Language:

english

File:

PDF, 546 KB

english, 2016

5

Tyrosinase Inhibitory and Anti-Tumor Promoting Activities of Compounds Isolated from Safflower (Carthamus Tinctorius L.) and Cotton (Gossypium Hirsutum L.) Oil Cakes

Nagatsu, Akito, Zhang, Hui, Mizukami, Hajime, Okuyama, Harumi, Sakakibara, Jinsaku, Tokuda, Harukuni, Nishino, Hoyoku

Journal:

Natural Product Letters

Year:

2000

Language:

english

File:

PDF, 460 KB

english, 2000

6

Cholesterol Issues in Japan Why Are the Goals of Cholesterol Levels Set So Low?

Hamazaki, Tomohito, Okuyama, Harumi, Ogushi, Yoichi, Hama, Rokuro

Journal:

Annals of Nutrition & Metabolism

Year:

2013

Language:

english

File:

PDF, 147 KB

english, 2013

7

Effect of dietary α-linolenate/linoleate balance on leukotriene production and histamine release in rats

Atsushi Hashimoto, Masahiro Katagiri, Shinpei Torii, Junichi Dainaka, Atsushi Ichikawa, Harumi Okuyama

Journal:

Year:

1988

Language:

english

File:

PDF, 849 KB

english, 1988

8

Hypertension in rats does not potentiate hypercholesterolemia and aortic cholesterol deposition induced by a hypercholesterolemic diet

Hiromi Mori, Kyohko Ishiguro, Harumi Okuyama

Journal:

Year:

1993

Language:

english

File:

PDF, 567 KB

english, 1993

9

Increased intake of n-3 polyunsaturated fatty acids elevates the level of apoptosis in the normal sigmoid colon of patients polypectomized for adenomas/tumors

Jinglei Cheng, Kumiko Ogawa, Kiyonori Kuriki, Yoshifumi Yokoyama, Takeshi Kamiya, Kyoji Seno, Harumi Okuyama, Jingwen Wang, Chenhong Luo, Toshiko Fujii, Hiromitsu Ichikawa, Tomoyuki Shirai, Shinkan To

Journal:

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

10

Testosterone-lowering activity of canola and hydrogenated soybean oil in the stroke-prone spontaneously hypertensive rat

Okuyama, Harumi, Ohara, Naoki, Tatematsu, Kenjiro, Fuma, Shinya, Nonogaki, Tomoyuki, Yamada, Kazuyo, Ichikawa, Yuko, Miyazawa, Daisuke, Yasui, Yuko, Honma, Seijiro

Journal:

The Journal of Toxicological Sciences

Year:

2010

Language:

english

File:

PDF, 576 KB

english, 2010

11

Fatty Acid Synthetase as a Thermoreceptor in Candida utilis1

ITO, Yasuyuki, OH-HASHI, Yoshihiro, OKUYAMA, Harumi

Journal:

Journal of Biochemistry

Year:

1986

Language:

english

File:

PDF, 447 KB

english, 1986

12

Sesquiterpene glycosides from cotton oil cake

Hui Li Zhang, Akito Nagatsu, Harumi Okuyama, Hajime Mizukami, Jinsaku Sakakibara

Journal:

Year:

1998

Language:

english

File:

PDF, 332 KB

english, 1998

13

Docosahexaenoic acid-rich fish oil does not enhance the elevation of serum transaminase and liver triacylglycerol induced by carbon tetrachloride in mice

Satoshi Yasuda, Shiro Watanabe, Tetsuyuki Kobayashi, Harumi Okuyama

Journal:

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

14

Studies on lipid metabolism in Tetrahymena pyriformis: Properties of acyltransferase systems

Harumi Okuyama, Kazuyo Yamada, Yasunaga Kameyama, Hiroh Ikezawa, Hirofumi Fukushima, Yoshinori Nozawa

Journal:

Archives of Biochemistry and Biophysics

Year:

1977

Language:

english

File:

PDF, 745 KB

english, 1977

15

An enzymatic rationale for the randomization of the positional distribution of fatty acids in phospholipids of ascites hepatoma AH 130

Ryoji Takenaka, Makoto Inoue, Takamitsu Hori, Harumi Okuyama

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 1.01 MB

english, 1983

16

Similar changes in clinical and pathological parameters in Wistar Kyoto rats after a 13-week dietary intake of canola oil or a fatty acid composition-based interesterified canola oil mimic

Naoki Ohara, Yukiko Naito, Kikuko Kasama, Tomoko Shindo, Hiromichi Yoshida, Tomoko Nagata, Harumi Okuyama

Journal:

Food and Chemical Toxicology

Year:

2009

Language:

english

File:

PDF, 177 KB

english, 2009

17

Fatty acid composition of lipids in tongue and hindleg muscles of muscular dystrophic mice

Tomomichi Futo, Teruaki Hitaka, Takaharu Mizutani, Harumi Okuyama, Kimi Watanabe, Tsuyoshi Totsuka

Journal:

Journal of the Neurological Sciences

Year:

1989

Language:

english

File:

PDF, 400 KB

english, 1989

18

An Enzyme Immunoassay for Prostaglandin E2 Using Biotin-Prostaglandin B2 Conjugate as a Tracer.

WATANABE, Shiro, YOSHIDA, Chie, KOBAYASHI, Tetsuyuki, OKUYAMA, Harumi

Journal:

Biological & Pharmaceutical Bulletin

Year:

1997

File:

PDF, 466 KB

1997

19

Dietary intake of rapeseed oil as the sole fat nutrient in wistar rats - Lack of increase in plasma lipids and renal lesions -

Ohara, Naoki, Naito, Yukiko, Nagata, Tomoko, Tachibana, Shigehiro, Okimoto, Mari, Okuyama, Harumi

Journal:

The Journal of Toxicological Sciences

Year:

2008

Language:

english

File:

PDF, 103 KB

english, 2008

20

Lysosomal Enzyme Activities Are Decreased in the Retina and Their Circadian Rhythms Are Different from Those in the Pineal Gland of Rats Fed an α-Linolenic Acid–Restricted Diet

Ikemoto, Atsushi, Fukuma, Akiko, Fujii, Yoichi, Okuyama, Harumi

Journal:

Journal of Nutrition

Year:

2000

Language:

english

File:

PDF, 234 KB

english, 2000

21

Dietary Lipids Impacts on Healthy Ageing

Harumi Okuyama, Kazuyo Yamada, Daisuke Miyazawa, Yuko Yasui, Naoki Ohara

Journal:

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

22

Enzymatic basis for the formation of pulmonary surfactant lipids by acyltransferase systems

Harumi Okuyama, Kazuyo Yamada, Takaki Miyagawa, Masahiro Suzuki, Renuka Prasad, William E.M. Lands

Journal:

Archives of Biochemistry and Biophysics

Year:

1983

Language:

english

File:

PDF, 831 KB

english, 1983

23

Dietary fatty acids — The n-6n-3 balance and chronic elderly diseases. Excess linoleic acid and relative n-3 deficiency syndrome seen in Japan

Harumi Okuyama, Tetsuyuki Kobayashi, Shiro Watanabe

Journal:

Progress in Lipid Research

Year:

1996

Language:

english

File:

PDF, 3.69 MB

english, 1996

24

HIV-1 nef suppression by virally encoded microRNA

Shinya Omoto, Masafumi Ito, Yutaka Tsutsumi, Yuko Ichikawa, Harumi Okuyama, Andi Ebiamadon Brisibe, Nitin K Saksena, Yoichi R Fujii

Journal:

Year:

2004

Language:

english

File:

PDF, 2.01 MB

english, 2004

25

Composition and turnover of phospholipids and neutral lipids in human breast cancer and reference tissues

Sakai, Keiko, Okuyama, Harumi, Yura, Jiro, Takeyama, Hiromitsu, Shinagawa, Nagao, Tsuruga, Nobuatsu, Kato, Katsumi, Miura, Kaoru, Kawase, Kyohey, Tsujimura, Tohru, Naruse, Takayoshi, Koike, Akihiko

Journal:

Year:

1992

Language:

english

File:

PDF, 570 KB

english, 1992

26

Protein Carbonyl Content Roughly Reflects the Unsaturation of Lipids in Muscle but Not in Other Tissues of Stroke-Prone Spontaneously Hypertensive Strain (SHRSP) Rats Fed Different Fats and Oils.

SATO, Akira, HUANG, Min-Zhao, WATANABE, Shiro, OKUYAMA, Harumi, NAKAMOTO, Hideko, RADAK, Zsolt, GOTO, Sataro

Journal:

Biological & Pharmaceutical Bulletin

Year:

1998

File:

PDF, 1002 KB

1998

27

Novel antioxidants from roasted perilla seed.

NAGATSU, Akito, TENMARU, Kiyoshi, MATSUURA, Hidekazu, MURAKAMI, Nobutoshi, KOBAYASHI, Tetsuyuki, OKUYAMA, Harumi, SAKAKIBARA, Jinsaku

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1995

File:

PDF, 475 KB

1995

28

Dietary Canola and Soybean Oil Fed to SHRSP Rat Dams Differently Affect the Growth and Survival of Their Male Pups

Tatematsu, Kenjiro, Fuma, Shin-ya, Satoh, Junichi, Ichikawa, Yuko, Fujii, Yoichi, Okuyama, Harumi

Journal:

Journal of Nutrition

Year:

2004

File:

PDF, 135 KB

2004

29

A High α-Linolenate Diet Suppresses Antigen-Induced Immunoglobulin E Response and Anaphylactic Shock in Mice

Watanabe, Shiro, Sakai, Naomi, Yasui, Yoshihiro, Kimura, Yukiko, Kobayashi, Tetsuyuki, Mizutani, Takaharu, Okuyama, Harumi

Journal:

Journal of Nutrition

Year:

1994

Language:

english

File:

PDF, 1.40 MB

english, 1994

30

Effects of the temperature range and the lack of β-ketoacyl acyl-carrier protein synthase II on fatty acid synthesis in Escherichia coli K12 after shifts in temperature

Oh-hashi Yoshihiro, Okuyama Harumi

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1986

Language:

english

File:

PDF, 714 KB

english, 1986

31

[Methods in Enzymology] Prostaglandins and Arachidonate Metabolites Volume 86 || [48] Preparation and analysis of radiolabeled phosphatidylcholine and phosphatidylethanolamine containing 3H- and 14C-Labeled polyunsaturated fatty acids

Okuyama, Harumi

Year:

1982

Language:

english

File:

PDF, 390 KB

english, 1982

32

Dietary Docosahexaenoic Acid Increases Cerebral Acetylcholine Levels and Improves Passive Avoidance Performance in Stroke-Prone Spontaneously Hypertensive Rats

Masaru Minami, Shinichi Kimura, Toru Endo, Naoya Hamaue, Masahiko Hirafuji, Hiroko Togashi, Machiko Matsumoto, Mitsuhiro Yoshioka, Hideya Saito, Shiro Watanabe, Tetsuyuki Kobayashi, Harumi Okuyama

Journal:

Pharmacology Biochemistry and Behavior

Year:

1997

Language:

english

File:

PDF, 100 KB

english, 1997

33

Modifications of Nucleosides and Nucleotides. II. Reaction of Ethylene Oxide with 1-Methylcytosine

Mizuno, Hatsuhiko, Okuyama, Harumi, Hayatsu, Hikoya, Ukita, Tyunosin

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1964

File:

PDF, 811 KB

1964

34

Kinetic parameters of lysophospholipid acyltransferase systems in diet-induced modifications of platelet phospholipid acyl chains.

MURASE, SHIGEO, YAMADA, KAZUYO, OKUYAMA, HARUMI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 929 KB

1988

35

Effect of dietary essential fatty acids on pulmonary metastasis of ascites tumor cells in rats.

HORI, TAKAMITSU, MORIUCHI, ATSUKO, OKUYAMA, HARUMI, SOBAJIMA, TAKESHI, TAMIYA-KOIZUMI, KEIKO, KOJIMA, KIYOHIDE

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 498 KB

english, 1987

36

Lipid Nutrition for the prevention of Diabetes, Cardio-and Cerebrovascular Disease, and Chronic Kidney Disease－Hidden Causes

Okuyama, Harumi, Ohara, Naoki

Journal:

Journal of Lipid Nutrition

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

37

Effects of dietary docosahexaenoic acid on survival time and stroke-related behavior in stroke-prone spontaneously hypertensive rats

Masaru Minami, Shin-ichi Kimura, Toru Endo, Naoya Hamaue, Masahiko Hirafuji, Yoshio Monma, Hiroko Togashi, Mitsuhiro Yoshioka, Hideya Saito, Shiro Watanabe, Tetsuyuki Kobayashi, Harumi Okuyama

Journal:

General Pharmacology: The Vascular System

Year:

1997

Language:

english

File:

PDF, 760 KB

english, 1997

38

Acyl coenzyme A: Phospholipid acyltransferases in porcine platelets discriminate between ω-3 and ω-6 unsaturated fatty acids

Makoto Inoue, Shigeo Murase, Harumi Okuyama

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 748 KB

english, 1984

39

Regional differences of the mouse brain in response to an α-linolenic acid-restricted diet: Neurotrophin content and protein kinase activity

Daisuke Miyazawa, Yuko Yasui, Kazuyo Yamada, Naoki Ohara, Harumi Okuyama

Journal:

Year:

2010

Language:

english

File:

PDF, 307 KB

english, 2010

40

Dietary, but not Topical, Alpha-linolenic Acid Suppresses UVB-induced Skin Injury in Hairless Mice when Compared with Linoleic Acid

Naoya Takemura, Kazuhiko Takahashi, Hiroshi Tanaka, Yuka Ihara, Atsushi Ikemoto, Yoichi Fujii, Harumi Okuyama

Journal:

Photochemistry and Photobiology

Year:

2002

Language:

english

File:

PDF, 143 KB

english, 2002

41

Effect of dietary α-linolenate/linoleate balance on endotoxin-induced hepatitis in mice

Shiro Watanabe, Harumi Okuyama

Journal:

Year:

1991

Language:

english

File:

PDF, 577 KB

english, 1991

42

Exploration for unknown substances in rapeseed oil that shorten survival time of stroke-prone spontaneously hypertensive rats: Effects of super critical gas extraction fractions

Naoki Ohara, Yukiko Naito, Tomoko Nagata, Kenjiro Tatematsu, Shin-ya Fuma, Shigehiro Tachibana, Harumi Okuyama

Journal:

Food and Chemical Toxicology

Year:

2006

Language:

english

File:

PDF, 537 KB

english, 2006

43

Risks of diabetes mellitus and cancer caused by cholesterol lowering medications

Okuyama, Harumi, Hamazaki, Tomohito, Ogushi, Yoichi, Hama, Rokuro

Journal:

Lipid Technology

Year:

2014

Language:

english

File:

PDF, 248 KB

english, 2014

44

Canola and hydrogenated soybean oils accelerate ectopic bone formation induced by implantation of bone morphogenetic protein in mice

Hashimoto, Yoko, Mori, Mayumi, Kobayashi, Shuichiro, Hanya, Akira, Watanabe, Shin-ichi, Ohara, Naoki, Noguchi, Toshihide, Kawai, Tatsushi, Okuyama, Harumi

Journal:

Toxicology Reports

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

45

Antioxidative Compounds Isolated from Safflower (Cartthamus tinctorius L.) Oil Cake.

ZHANG, Hui Li, NAGATSU, Akito, WATANABE, Toshihiro, SAKAKIBARA,, OKUYAMA, Harumi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1997

File:

PDF, 838 KB

1997

46

Studies on the safety of perilla oil. Effects on reproduction and skeletal teratogenicity.

NAITO, Yukio, ISHIZAKI, Kaoru, YAMAMOTO, Hajimu, OKUYAMA, Harumi

Journal:

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)

Year:

1990

File:

PDF, 647 KB

1990

47

Erratum to ‘Increased intake of n-3 polyunsaturated fatty acids elevates the level of apoptosis in the normal sigmoid colon of patients polypectomized for adenomas/tumors’ [Cancer Letters 193 (2003) 17–24]

Jinglei Cheng, Kumiko Ogawa, Kiyonori Kuriki, Yoshifumi Yokoyama, Takeshi Kamiya, Kyoji Seno, Harumi Okuyama, Jingwen Wang, Chenhong Luo, Toshiko Fujii, Hiromitsu Ichikawa, Tomoyuki Shirai, Shinkan To

Journal:

Year:

2004

Language:

english

File:

PDF, 44 KB

english, 2004

48

Effects of dietary fats on senile amyloidosis in SAMP1 mice

Makiko Umezawa, Harumi Okuyama, Masanori Hosokawa, Toshio Takeda, Keiichi Higuchi

Journal:

International Congress Series

Year:

2004

Language:

english

File:

PDF, 68 KB

english, 2004

49

Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-β, fibronectin and renin

Makoto Miyazaki, Naoya Takemura, Shiro Watanabe, Noriaki Hata, Yoshihisa Misawa, Harumi Okuyama

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2000

Language:

english

File:

PDF, 318 KB

english, 2000

50

Regulation of membrane lipid synthesis in Escherichia coli after shifts in temperature

Okuyama, Harumi, Yamada, Kazuyo, Kameyama, Yasunaga, Ikezawa, Hiroh, Akamatsu, Yuzuru, Nojima, Shoshichi

Journal:

Year:

1977

Language:

english

File:

PDF, 696 KB

english, 1977

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